It follows a fading celebrity, Elisabeth Sparkle (Demi Moore) who, after being fired by her producer (Dennis Quaid) due to her age, uses a black market drug that creates a much younger version of herself (Margaret Qualley) with unexpected side effects.

Sep 20, 2024 · Demi Moore and Margaret Qualley had a personal connection offscreen long before sharing one onscreen in their new movie The Substance.

Sep 20, 2024 · The Substance: Directed by Coralie Fargeat. With Demi Moore, Margaret Qualley, Dennis Quaid, Edward Hamilton-Clark. A fading celebrity takes a black-market drug: a cell-replicating substance that temporarily creates a younger, better version of herself.

Jan 5, 2025 · 'The Substance' stars Demi Moore and Margaret Qualley reprised their roles from the horror film to present the Golden Globe for Best Male Actor TV.

Sep 23, 2024 · How ‘The Substance’ Pulled Off That Bloody, Gloriously Disgusting Ending With Demi Moore and Margaret Qualley

Nov 26, 2024 · Margaret, did you get the chance to do any prep work with Demi prior to filming the film? And how were there discussions between the two of you regarding the movie and your roles? Margaret Qualley:

Sep 21, 2024 · Margaret Qualley can be quite the monster when she needs to be. Demi Moore endured her share of makeup wizardry in the body horror movie “The Substance," playing an aging TV fitness celebrity...

Sep 17, 2024 · In Coralie Fargeat’s body horror shocker The Substance, Demi Moore stars as Elisabeth Sparkle, a former A-lister who is unceremoniously fired from her fitness TV show by a loathsome studio...

Sep 6, 2024 · Demi Moore bravely weathered Dennis Quaid wolfing down shrimp for "The Substance," her wild new body horror movie with Margaret Qualley.

2 days ago · How ‘The Substance’ Makeup Team Turned Demi Moore and Margaret Qualley Into “Monstro Elisasue” (Exclusive Photos) Prosthetics boss Pierre Olivier Persin, now an Oscar nominee for his work ...