Aim Following the publication of the updated NICE guidelines1 recommending the use of standardised parenteral nutrition (PN) in preterm and term babies, alongside the known associated risks to patient ...

Objectives Blood cultures are the first-line tool for diagnosis of bloodstream infections. Their diagnostic value, however, may be affected when a microorganism of questionable evidence is isolated.

Sepsis is an important global health issue that is estimated to affect more than 25 million children per year worldwide and results in 3.4 million deaths, predominantly in children younger than 5 ...

Objective Children with Kawasaki disease (KD) and an initial echocardiogram that demonstrates coronary artery aneurysms (CAAs, Z score ≥2.5) are at high risk for severe cardiovascular complications.

Background Recruitment of paediatric trainees is not matching its increasing demand. In 2019, only 69.8% of paediatric training program posts were filled, the lowest out of all UK programmes. Such ...

The recent epidemic of childhood obesity[1][1] has raised concern because of the possible clinical and public health consequences.[2,][2][3][3] However, there remains a widespread perception among ...

Background: Difficulty falling asleep (prolonged sleep latency) is a frequently reported problem in school-aged children. Aims: This study aimed to describe the distribution of sleep latency and ...

Aims Throughout the Covid-19 pandemic, several working practices were changed to allow for better infection control awareness and practice. St Richard’s Hospital paediatric department adopted the use ...

Objective To determine the association of initial empiric antibiotic regimens with clinical outcomes in hospitalised children with severe orbital infections. Design Multi-centre observational cohort ...

Introduction Autosplenectomy defines spontaneous splenic infarction leading to hyposplenism. It occurs mainly as a complication of sickle cell anemia, pneumococcal sepsis or systemic lupus ...

Attention deficit hyperactivity disorder (ADHD) affects around 1–3% of children. There is a high level of comorbidity with developmental and learning problems as well as with a variety of psychiatric ...

Objective The β2-agonists such as salbutamol are the mainstay of asthma management. Pharmacokinetic–pharmacodynamic (PKPD) models to guide paediatric dosing are lacking. We explored the relationship ...