The media queen also confessed that she was reluctant to take a GLP-1 drug because she felt it was “the easy way out.” That changed after a special on weight loss with experts and clinicians that she taped in July 2023. The panel discussion left her with her “biggest aha moment” about the medication.

Oprah Winfrey shared that weight-loss medications like Ozempic and Wegovy helped her understand the challenges of being thin. After losing nearly 50 pounds, she emphasized that these drugs assist in managing cravings and support a healthier lifestyle amidst her struggles with weight.