The main objective of the present study was to explore the differential impact of a single dose of ketamine or esketamine on BDNF serum levels in TRD subjects. We also aimed to evaluate the ...

Good morning, it’s the third of July. This newsletter will be off tomorrow for the holiday and — surprise — all of next week.

Ketamine has been making headlines for years, from the death of actor Matthew Perry to Elon Musk's reported microdosing, to its portrayal in Hulu's "The Secret Lives of Mormon Wives." ...

The effects of esketamine were seen at 24 hours and could last up to four weeks with repeated doses. Esketamine caused a lot more side effects than placebo. The certainty of evidence varied ...

N-methyl-D-aspartate (NMDA) antagonists, such as ketamine and its enantiomers, S (+)-ketamine (esketamine) and R (-)-ketamine (arketamine), have demonstrated a robust antidepressant effect and ...