Studies about tenecteplase are emerging and, globally, more than 20 trials have been completed or are ongoing. The phase 3 trials AcT (Intravenous Tenecteplase Compared With Alteplase for Acute ...

The ACC/AHA Task Force on Clinical Practice Guidelines (Task Force) continuously reviews, updates, and modifies guideline methodology on the basis of published standards from organizations including ...

Valvular repair or replacement is a common final management option in both primary and secondary MR, resulting in ≈50 000 annual mitral valve operations in the United States; however, defining the ...

As early as 1699, Chemineau described a heart composed of 2 auricles but only 1 ventricle.1 The univentricular heart has since fascinated the medical community. Unique in its complexity and scope, the ...

Aim: This executive summary of the clinical practice guideline for the evaluation and diagnosis of chest pain provides recommendations and algorithms for clinicians to assess and diagnose chest pain ...

Adenoviruses are typically associated with mild respiratory infections, but are increasingly attributed to cardiac infection. Viruses have long been understood to infect the heart, with many studies ...

The central antihypertensive action of clonidine was established by Sattler and van Swieten 1 in 1967. In their report, they described how this α 2-adrenergic agonist produced a depressor effect when ...

A comprehensive literature search was conducted from September 14, 2022, to November 22, 2022, encompassing studies, reviews, and other evidence on human subjects that were published in English from ...

Beginning in this issue of Circulation, we present two new features designed to enhance the transfer of information to our clinician readers. First, you will notice that the cover includes a new box ...

The interesting results of Ciaccio et al 15 may be seen as an attempt to support the notion that as AF becomes persistent, it increasingly depends on drivers localized within atrial regions outside ...

Background— The relationship of circulating levels of high-sensitivity C-reactive protein (CRP) with cardiovascular disease (CVD) risk, particularly with consideration of effects at intermediate ...