While the U.S. insists it is not involved in strikes on Iran, American officials have confirmed military forces have been helping to intercept Iranian missiles fired at Israel.

Israel and Iran exchange missile attacks for a third day; nuclear sites hit, death tolls rise, airspace shut, U.S. warns Tehran against retaliation.

Former Vice President Mike Pence said on “State of the Union” Sunday that if Israel’s attack doesn’t somehow convince Iran to make major concessions in Trump’s diplomatic attempt to end its nuclear program, then the United States should be prepared to join the conflict.

President Donald Trump rejected an Israeli plan in recent days to kill Iran's Supreme Leader Ayatollah Ali Khamenei, two U.S. officials told ABC News. The officials stated that Israel shared with the United States that they had a window to kill Iran's leader but the president was not on board with the plan.

With Israel’s strikes on the Iranian nuclear sites, Prime Minister Benjamin Netanyahu might have played the gamble of his life. Without US involvement, it appears highly improbable for Israel to destroy Iran’s nuclear capabilities — the main objective of the war.

The conflict, the most intense fighting between the two countries in decades, has been met in the United States with feelings of “frustration and helplessness,” as well as heartbreak.

Experts suggest the U.S. has a strategic opportunity to leverage Iran's weakened position for a nuclear deal after Israel's targeted strikes on Iranian nuclear and military sites.

Israel warns "Tehran will burn" if Iran continues firing missiles, while state media say 60 people have been killed in a strike on Iran's capital.