Israel and Iran have opened a new chapter in their long history of conflict when Israel launched a major attack with strikes early Friday on Tehran.

Israel hit more targets in Tehran and Iranian missiles fired at Israel killed at least 10, as the conflict entered a third day

The "America First" president praised his foreign policy record on Sunday while urging a deal between Iran and Israel amid escalating strikes.

Regime change in Iran could be a result of Israel's military attacks on the country, Israeli Prime Minister Benjamin Netanyahu told Fox News on Sunday, saying Israel would do whatever is necessary to remove the "existential threat" posed by Tehran.

DUBAI, United Arab Emirates (AP) — Israel launched an expanded assault on Iran on Sunday, with direct strikes targeting its energy industry and Defense Ministry headquarters, while Tehran unleashed a fresh barrage of missiles blamed for the deaths of four people and injuries of many others.

The Israeli military struck "over 170 targets" in Iran in three days, the Israel Defense Forces (IDF) said on Sunday.

Several people were killed when Iran fired a barrage of projectiles at Israel in retaliation for Israel's surprise attack on its foe’s nuclear facilities and military leadership. Follow along for live updates,

Israel warns "Tehran will burn" if Iran continues firing missiles, while state media say 60 people have been killed in a strike on Iran's capital.