The 49ers are hurting right now, with stars Christian McCaffrey and Deebo Samuel set to miss Sunday's NFC West clash against ...

If Kittle does miss Sunday's game, he will join star running back Christian McCaffrey, who is currently on the Injured ...

The San Francisco 49ers started off Week 3 on the right foot. After absences and limited participations littered their first ...

Defensive coordinator Nick Sorensen and run game coordinator and offensive line coach Chris Foerster reviewed the 49ers ...

San Francisco 49ers tight end George Kittle may miss Week 3's matchup with the Los Angeles Rams after missing Thursday's ...

San Francisco 49ers tight end George Kittle might miss Week 3's game with a hamstring. View the 49ers TE depth chart inside.

With McCaffrey and Samuel out, Rams brace for 49ers' cunning tactics. Kobie Turner stresses the need for execution.

George Kittle and Charvarius Ward not practicing Thursday could mean the San Francisco 49ers will be missing four All-Pros ...

San Francisco 49ers quarterback Brock Purdy isn't letting early-season injuries shake his confidence. Although he has been ...

The Niners are lost All-Pro running back Christian McCaffrey and star receiver Deebo Samuel to injuries before Kittle ...

As the San Francisco 49ers set their sights on another deep playoff run this season, wide receiver Deebo Samuel is making one ...

Deebo Samuel is nursing a strained calf, but that isn't stopping him from speaking his truth. The San Francisco 49ers star ...