In the second paper, the researchers explore how ecDNA is copied and inherited during cell replication. Surprisingly, ecDNAs ...

Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...

These findings suggest that KIR2DS2-positive (KIR2DS2+) natural killer (NK) cells could be an attractive therapeutic target ...

In this valuable study, Li and others identified cell membrane receptors for juvenile hormone (JH), a terpenoid hormone in insects that regulates their development and reproduction. While ...

The adrenal glands are two small glands located on top of the kidneys. They produce hormones that help regulate heart rate, blood pressure, the immune system, physical stress response, and other ...

To ensure that the CAR-T cells only target tumor cells, the Geneva team first tested them in vitro on both healthy and diseased cells. “We were pleasantly surprised to find that not only did CAR-T not ...

Menopausal hormone therapy (MHT) was popular in the 1990s before the publication of a study in the early 2000s saw its use rapidly plummet. Today, having recovered from some misreporting around ...

In response to incoming food, these hormones are secreted by rare hormone producing cells in the gut and play key roles in managing digestion and appetite. The intestine acts as a vital barrier.

One of these compounds effectively kills colorectal cancer cells by attacking the enzyme DCTPP1, which thus may serve as a potential biomarker for colorectal cancer and a therapeutic target.

ZEN is so structurally like the hormone 17β-estradiol that it binds ... increase as we get warmer temperatures and weather." Some cell studies suggest ZEN may be more potent than other known ...