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The US FDA has granted orphan drug designation (ODD) to Modalis Therapeutics’ MDL-101, aimed at treating LAMA2-CMD.
Under the revised agreement, both companies will co-develop four Radio-DARPin programs; each company will have the right to commercialize two programs (previously one each)Molecular Partners will hold ...
Transcription activation of genes by estrogens is driven by enhancers, which are often located within the same Topologically Associating Domain (TAD) as non-targeted promoters. We investigated how ...
Zettabytes—that’s 10 21 bytes—of data are currently generated every year. All of those cat videos have to be stored somewhere, and DNA is a great storage medium; it has amazing data density ...
Synthetic genes, though few, can generate complex biomolecular materials when their expression is part of a temporal control ...
What is DNA, and how does it work? You don't need a degree in genetics to understand. Here, we'll give an overview of DNA and ...
Tiny circles called ecDNA are critical in cancer development and drug resistance. An international team publishes landmark studies detailing new findings and potential therapies.
This important manuscript provides insights into the competition between Splicing Factor 1 (SF1) and Quaking (QKI) for binding at the ACUAA branch point sequence in a model intron, regulating exon ...