A 79-year-old man was admitted to a hospital in Guangzhou, China, with progressive dyspnea and edema. Echocardiography and ...

Patients with severe hypertriglyceridemia have an increased risk of acute pancreatitis. The efficacy and safety of olezarsen, ...

The benefit of beta-blockers after myocardial infarction in patients with a preserved left ventricular ejection fraction ...

Despite guideline recommendations, evidence for the use of non–vitamin K antagonist oral anticoagulant (NOAC) monotherapy in ...

Icotrokinra, a targeted oral peptide that selectively binds the interleukin-23 receptor, is under investigation for the ...

Both tobevibart (a monoclonal antibody) and elebsiran (a small interfering RNA) target hepatitis B virus surface antigen ...

Fifty years ago, Henry Beecher warned about serious problems with human-subjects research in the United States and exhorted researchers to reform. Research regulations proliferated in the ensuing ...

The most important attribute of patient-centered care is the active engagement of patients when fateful health care decisions must be made — when they arrive at a crossroads of medical options, where ...

Opioid deprescribing is advised when risks of opioid use outweigh benefits. A tailored, patient-centered plan with gradual dose reduction, monitoring, and support can improve outcomes and reduce harm.

Countries that rely more on price regulation and public financing might be expected to be less vulnerable to corporate influences in health care. But private equity firms are making inroads in vari ...

The cytokine A proliferation-inducing ligand (APRIL) is considered a key driver of the pathogenesis of IgA nephropathy. Sibeprenlimab, a humanized IgG2 monoclonal antibody, selectively binds to and ...

Two patients had autoimmune hemolytic anemia that relapsed after CD19 CAR T-cell therapy but responded rapidly to BCMA-targeted T-cell–engager therapy with remission, minimal side effects, and hema ...