The landscape of peptide-based research continues to broaden as investigators pursue compounds capable of interacting with molecular networks involved in cellular communication, structural maintenance ...

Viruses attack nearly every living organism on Earth. To do so, they rely on highly specialized proteins that recognize and ...

The behaviour of a receptor protein can be influenced by the presence of certain lipids in the membrane it is embedded in.

Drug discovery requires two separate steps: checking whether a drug can bind to a harmful molecule or its receptor, and ...

A new study found that a single mutation to the hemagglutinin protein of an H5N1 virus isolated from a dairy worker in Texas this spring switched the protein’s binding specificity from avian- to human ...

The ability to grow stem cell-derived biological tissues, such as skin and other organs, in the laboratory holds promise for applications in areas including wound healing and transplants. However, ...

Scientists are aiming to determine the composition and topology of physiological Ashwell-Morell receptor ligands. Their findings will help uncover the receptor's still-hidden secrets. After earning ...

A new study reveals a critical vulnerability in a brain receptor targeted by a rare autoimmune disease. Researchers have moved a step closer to new treatments for a rare and often devastating ...

A new editorial paper was published in Oncoscience, titled "PH-binding motifs as a platform for drug design: Lessons from protease-activated receptors; PARs." While targeted cancer therapy is greatly ...

"To provide direct evidence for binding of the molecule at different pockets of the receptor, we have developed a new assay, which enables us to measure the binding specifically at the extracellular ...