Wildlife officials in the U.S. and Canada report cases of chronic wasting diseases where it hasn't been detected before.

Scientists have detected abnormal prion protein in the skin of several people who died from Creutzfeldt-Jakob disease (CJD). The scientists also exposed healthy mice to skin extracts from two CJD ...

We may have been overestimating the role of a pathological class of misfolded protein in neurodegenerative disease. Called prions, these molecules are responsible for conditions such as bovine ...

Prion diseases are a group of human and animal neurodegenerative conditions that have in common a key role for the prion protein in their pathogenesis. Traditionally, human prion diseases are ...

Prion Disease is currently an invariably fatal condition without treatment or cure. Despite multiple prior treatment studies, including quinacrine, doxycycline, and pentosan polysulfate, no ...

The misfolding of proteins and their subsequent deposition as amyloid in peripheral nerves lead to sensory and autonomic neuropathy A new hereditary form of neuropathy, prion protein (PrP) systemic ...

Sporadic CJD (sCJD) Unknown, but widely believed to be due to a spontaneous misfolding of the normal prion protein. Affects mainly people over the age of 60. Common symptoms include ataxia and ...

Prion diseases are progressive nervous system diseases which always have a fatal outcome. They are transmissible and affect many mammals. They are also called transmissible spongiform encephalopathies ...

Researchers have synthesized the first artificial human prion, a dramatic development in efforts to combat a devastating form of brain disease that has so far eluded treatment and a cure. Case Western ...

The virus causing the ongoing COVID-19 pandemic, SARS-CoV-2, has spread far more quickly than any other coronavirus in recorded history. Why is it so contagious? One possibility is that its spike ...