Insulin is one of the most potent and pleiotropic hormones in the body, regulating a myriad of physiological processes. However, perhaps none is best studied as its role in regulating glucose ...

The hormone adrenomedullin disrupts insulin signaling in blood vessel cells, contributing to systemic insulin resistance in obesity-associated type 2 diabetes, according to a new study. Blocking ...

Obesity has become a global epidemic affecting diverse populations and leading to metabolic syndrome across different sexes and age groups. A significant aspect of obesity is the development of leptin ...

Rutgers Robert Wood Johnson Medical School and collaborating institutions have found that overnutrition leads to insulin resistance and metabolic disorders through increased activity of the ...

Saturated fats are often discussed mainly for their role in raising LDL cholesterol, but research shows their metabolic ...

Three years ago, the inceptor protein was discovered and its role as an inhibitor of the insulin signaling pathway was described. Inceptor and the insulin receptor are located on the surface of beta ...

Developing resistance to insulin is a key step on the road to diabetes, making insulin resistance a target for treating metabolic dysfunction. Insulin orchestrates blood glucose levels by signaling ...

Protein intake influences far more than muscle mass; it shapes vascular function and pancreatic insulin dynamics over time.

This review examines how GLP-1 receptor agonists may influence neurodegenerative disease biology through metabolic, ...

Eating certain foods, such as hot dogs, added sugars, French fries, excessive alcohol, high-sodium diets, and artificial sweeteners, can increase inflammation, impair blood flow, disrupt insulin ...

Willpower is not purely a personality trait. Aging, obesity, insulin resistance, and inflammation may impair frontal brain ...