Cells have an internal skeleton that maintains their structure and also drives their movement. Known as the cytoskeleton, ...

Researchers used cryo-EM to study how the HIV enzyme integrase arranges in 3D to slip its DNA into the host genome and pack its genetic material into new viral particles.

The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the ...

The endoplasmic reticulum (ER) is a crucial organelle present in eukaryotic cells, including human cells. The ER plays a vital part in making sure proteins are properly constructed, and that they get ...

As a hematologist and physician-scientist who specializes in bone marrow transplantation, Dr. Albert Yeh describes the “holy grail” of transplantation biology that has yet to be answered: “how do you ...

As a grad student in cell biology, Shaeri Mukherjee was always on the lookout for new ways to fiddle with cells’ internal structures. It was the early 2000s, and Mukherjee was working in Dennis ...

Host cells that are modified to express therapeutic proteins are the foundation of the biopharmaceutical industry. However, these cells also express proteins other than the ones they’re supposed to ...

It was during one of these experiments that they saw a hitherto unobserved structure emerging from the cell. Looking like a twisted fiber, called a cilium, it extended into the mass of surrounding ...

According to estimates, about a third of the world's population is infected with the single-celled parasite Toxoplasma gondii, the pathogen of toxoplasmosis. Although harmless for most people, the ...