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New structure gives insight into mRNA export and cancers, and how viruses hijack the process to infect their host
The central dogma of biology defines the flow of genetic information: It describes how proteins are made from mRNA templates, which are in turn made from DNA. Exporting the mRNA from inside the ...
It was during one of these experiments that they saw a hitherto unobserved structure emerging from the cell. Looking like a twisted fiber, called a cilium, it extended into the mass of surrounding ...
The endoplasmic reticulum (ER) is a crucial organelle present in eukaryotic cells, including human cells. The ER plays a vital part in making sure proteins are properly constructed, and that they get ...
Researchers used cryo-EM to study how the HIV enzyme integrase arranges in 3D to slip its DNA into the host genome and pack its genetic material into new viral particles.
As a grad student in cell biology, Shaeri Mukherjee was always on the lookout for new ways to fiddle with cells’ internal structures. It was the early 2000s, and Mukherjee was working in Dennis ...
As a hematologist and physician-scientist who specializes in bone marrow transplantation, Dr. Albert Yeh describes the “holy grail” of transplantation biology that has yet to be answered: “how do you ...
According to estimates, about a third of the world's population is infected with the single-celled parasite Toxoplasma gondii, the pathogen of toxoplasmosis. Although harmless for most people, the ...
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