The discovery of Hoogsteen base pairs, an alternative pairing mode to the canonical Watson–Crick structure, has significantly broadened our understanding of DNA dynamics. This conformation, in which ...
The majority of base pairs in double-stranded DNA exist in the canonical Watson-Crick geometry. However, they can also adopt alternate Hoogsteen conformations in various complexes of DNA with proteins ...
The Nature Index 2025 Research Leaders — previously known as Annual Tables — reveal the leading institutions and countries/territories in the natural and health sciences, according to their output in ...
Researchers have developed a method to program the spatial organization of double-stranded DNA by incorporating Hoogsteen interactions. Researchers at Aarhus University (Denmark) have developed a ...
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