Gene expression and features of the DNA–protein complex chromatin were mapped together at high spatial resolution in tissue sections of the mouse or human brain. This spatially resolved technology ...
The central focus of exploring regulatory elements in mRNA has been on sequence-specific RNA-binding proteins (RBPs) that influence mRNA stability, translation, and splicing. On the other hand, some ...
A team of researchers from Yale and the Karolinska Institutet in Sweden developed novel technology that is the first to map genome-wide gene regulation in tissue. Every cell in the human body has the ...
The COVID-19 pandemic has highlighted how our small genetic differences can have a tremendous effect on how our bodies respond to disease. Researchers have created 3D maps of how enhancer sequences ...
A research team has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena such as cancer development, metastasis, tissue differentiation from stem ...
Bread, beer, and wine might be the tastiest and most tangible contribution that yeast has provided the world, but its impact on advancing knowledge in the biological sciences is perhaps its most ...
A new multimodal atlas constructed by researchers at the Massachusetts Institute of Technology reveals that the progression of Alzheimer’s disease involves widespread changes in the regulation of gene ...
A gene therapy allows precise magnetic field control of specific brain circuits without implanted devices. The image shows restricted mRNA expression of the genetically encoded magnetic sensor (red) ...
In a recent study published in Nature Communications, researchers described an approach to edit the recombination-activating gene 2 (RAG2) locus for therapeutic applications. Study: CRISPR-Cas9 ...
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