A new research paper was published in Oncotarget, titled, "Polyisoprenylated cysteinyl amide inhibitors deplete singly polyisoprenylated monomeric G-proteins in lung and breast cancer cell lines." ...

Researchers have developed a novel technique that allows them to dial up or tone down the amount of a certain metastatic protein inhibitor (BACH1) within a cell. This could provide a new path in ...

A new review reveals how focal adhesion kinase (FAK) acts as a central regulator of tumor progression and immune suppression ...

The innate immune system is the first responder to disease or infection. The body employs non-specific immune cells to recognize foreign pathogens and immediately target these invaders by promoting an ...

A new comprehensive review is shedding light on the expanding role of focal adhesion kinase (FAK) in cancer biology and its potential as a ...

Targeted inhibition of a "signal jammer" protein may improve how tumors respond to immunotherapy. Published today in Nature, a new study demonstrates how some cancer cells use the protein ...

An illustration shows the structure of an inhibitor bound to the active site of membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase. An inhibitor bound to the active site of ...