In eukaryotes, the tight or loose packaging of the genes in chromatin (DNA plus specific proteins) can control whether the genes can be expressed to form their encoded product. Chromatin is usually ...
Transcription by Pol II is dependent on a number of multi-subunit complexes including TFIID, a general transcription factor complex, and SAGA. Both deliver the TATA-box binding protein (TBP) to ...
The field of epigenetics is progressing rapidly and becoming indispensable to the study of fundamental gene regulation. Recent advances are redefining our understanding of core components that ...
A newly discovered promoter element "start" points to a shared regulatory syntax for controlling transcription initiation in bacteria, archaea, and eukaryotes.