A Northwestern Medicine study has revealed a previously unknown connection between two fundamental cellular processes, ...
In a recent study published in the journal Nature, researchers identify the mechanisms through which double-stranded break (DSB)-induced compartment formation orchestrates the deoxyribonucleic acid ...
This Brush Up is sponsored by Cayman Chemical. Learn more about chemical inhibitors of histone modification. Histone modification affects how tightly DNA wraps around histone proteins, yielding ...
The upper right portion illustrates viral nucleosome-like particles formed by co-occurring viral histone triplets and singlets. On the lower right, a network depicts distinct types of viral ...
A research team led by Dr Gary Ying Wai CHAN from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed the function of a unique enzyme, ANKLE1. ANKLE1 acts on chromatin ...
If parent cells and their daughter cells are to share a stable identity, parent cells must divide—and replicate their DNA—while ensuring that their histones are distributed properly to their daughter ...
Originally isolated from soil microbes, “anthracyclines rapidly made their way to the clinic and are still one of the most effective compounds we have today,” explained Dr. Matthew Wooten, a ...
The researchers found that, contrary to how it’s depicted in most textbooks, chromatin does not fold in on itself in an organized manner to create distinct structures. Instead, it forms a pliable, ...
One of the most detailed 3D maps of how the human chromosomes are organized and folded within a cell's nucleus is published in Nature.
This article was originally featured on Knowable Magazine. Every second, as we breathe, sleep, eat and go about our lives, millions of biochemical reactions are happening in our cells. Among the hurly ...
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