Mammalian transmissible spongiform encephalopathy (prion) and amyloid diseases seem to involve the self-propagation of abnormal fibrillar or sub-fibrillar protein aggregates. Similar processes explain ...

New research from Japan suggests that a rare brain-destroying disease caused by rogue prion proteins may be becoming more common—likely due to an aging population. The study, published last month in ...

Affecting both people and animals, prion diseases are degenerative brain disorders that can debilitate or kill their victims. The most common form of prion disease affecting humans is sporadic ...

In a new study, researchers from Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease. This insight, ...

How the infectious proteins behind BSE (mad-cow disease) jumped a species barrier to cause the recent outbreak of variant Creutzfeld-Jakob disease is still something of a mystery. Now researchers have ...

Many neurodegenerative diseases involve a common pattern of protein misfolding, aggregation, and toxicity. Though the identity of the actual polypeptide varies for each disease, the outcome converges ...

Prion diseases are progressive nervous system diseases which always have a fatal outcome. They are transmissible and affect many mammals. They are also called transmissible spongiform encephalopathies ...

The brains of people with Down syndrome develop the same neurodegenerative tangles and plaques associated with Alzheimer's disease and frequently demonstrate signs of the neurodegenerative disorder in ...

Alfredo has a PhD in Astrophysics and a Master's in Quantum Fields and Fundamental Forces from Imperial College London.View full profile Alfredo has a PhD in Astrophysics and a Master's in Quantum ...

People with the rare and fatal brain disorder Creutzfeldt-Jakob disease (CJD) show signs of the disease in their eyes, according to a new study. The study found evidence of prions — the infectious ...

On Tuesday (July 27), five public research institutions in France announced they will suspend research on prions for three months. According to their joint press release, the decision was spurred by a ...