Several specific genetic mutations have been associated with colorectal cancer (CRC) and dysplasia in patients with ulcerative colitis (UC). [1] Many of these genetic alterations are unique to ...

Scientists at Weill Cornell Medicine have finally found a way to correlate mutations with observable characteristics in human cells, taking a step towards understanding how diversified mutations in ...

Tumor-infiltrating clonal hematopoiesis increased the risk of disease recurrence or death among patients with cancer. TET2 mutations were the strongest genetic predictor of tumor-infiltrating clonal ...

Gemogenovatucel-T is a DNA-engineered, triple-function immunotherapy that utilizes a patient's autologous tumor cells as a source for the complete matrix of tumor-related clonal signals. Its mechanism ...

Risks of Organ Preservation in Rectal Cancer: Data From Two International Registries on Rectal Cancer Authors retain all rights in any data supplements associated with their articles The ideas and ...

A review examines the prevailing theory of cancer evolution. The authors highlight both practical and theoretical limitations of the clonal model of cancer evolution and propose areas for improving ...

Please provide your email address to receive an email when new articles are posted on . Clonal hematopoiesis occurred at similar rates among donors and recipients over decades. Findings suggest older ...

Cells from cancerous tumors can spread, or metastasize, throughout the body. Researchers have long sought to understand what ...

A recent review by Carlo Maley, a researcher at Arizona State University, and Lucie Laplane from the University of Paris Pantheon-Sorbonne critiques the dominant theory of cancer evolution. The ...