Bacterial topoisomerase inhibitors represent a promising class of antimicrobial agents that target essential enzymes involved in DNA replication and maintenance. By inhibiting enzymes such as DNA ...

Two bacteria are sitting near free-floating DNA. Suddenly, one bacterium shoots out a long appendage, latches onto a DNA fragment and reels in its catch. It happens fast, but it’s clear: this organism ...

Researchers from Durham University, Jagiellonian University (Poland) and the John Innes Centre have achieved a breakthrough in understanding DNA gyrase, a vital bacterial enzyme and key antibiotic ...

A research team at the Hebrew University has shown that bacteria can survive antibiotic exposure via two distinct ...

Microbiologists have long known that ancient, inactive viruses known as cryptic prophages can insert their genetic material into bacterial DNA. These genetic fragments allow bacteria to use ...

Researchers at the Francis Crick Institute and UCL have analyzed ancient DNA from Borrelia recurrentis, a type of bacteria that causes relapsing fever, pinpointing when it evolved to spread through ...

A new technique, which involves melting bacterial DNA found in blood samples, could deliver diagnoses of potentially fatal infections faster than ever before. Results may be obtained in a few hours, ...

As the number of antibiotic-resistant infections continues to rise, scientists are looking to bacteriophages (“phages”), viruses that infect bacteria, as an approach to tackling antibiotic resistance.

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable bacterial product causes mutations in DNA that have been linked to ...

Researchers from Pasadena-based California Institute of Technology developed a new test that can pinpoint antibiotic-resistant bacteria within half an hour. The researchers published their findings in ...